“Microdose” GLP-1 programs sell compounded semaglutide or tirzepatide at doses below the usual treatment range. Published prices run from $79 to $199 a month: CoreAge Rx is cheapest, bmiMD sits in the middle, and SHED and Lemonaid cost the most. Before you compare prices, know that no clinical trial has tested GLP-1 microdosing as these programs market it, and the benefits on their pages are claims, not proven results.
Microdose GLP-1 prices (checked October 24, 2026)
| Provider | Semaglutide | Tirzepatide |
|---|---|---|
| CoreAge Rx | From $79 a month | From $129 a month |
| PlexusDx | $99 a month; $69 on a 12-month plan | $99 a month; $69 on a 12-month plan |
| bmiMD | $119 a month (3-month plan) | $159 a month (3-month plan) |
| SHED | From $149 a month | From $199 a month |
| Gala Health | Not listed separately | $149 a month (GLP-1/GIP, yearly plan) |
| Lemonaid Health | $199 a month + $49 membership | $199 a month + $49 membership |
Source: each provider’s own microdose pages, read October 24, 2026. Compounded medications are not FDA-approved.
What this covers
Prices and plan terms
| Provider | Semaglutide microdose | Tirzepatide microdose | Plan terms |
|---|---|---|---|
|
CoreAge Rx Check price ↗ affiliate link | From $79 a month | From $129 a month | “No long-term contracts.” CoreAge says the price stays the same at every dose. |
|
PlexusDx Check price ↗ affiliate link | $99 a month ($89, $79 or $69 on 3-, 6- or 12-month plans) | $99 a month ($89, $79 or $69 on 3-, 6- or 12-month plans) | Same price at every dose: 0.05 to 0.25 mg of semaglutide or 1 to 2.5 mg of tirzepatide a week. $0 charged unless a provider approves. Checked October 26, 2026. |
|
bmiMD Semaglutide microdose ↗ affiliate link Tirzepatide microdose ↗ affiliate link | $119 a month on a 3-month plan ($357 total; list price $229) | $159 a month on a 3-month plan ($477 total; list price $349) | Subscribe-and-save plans of 1, 3, 6 or 12 months; full refund if a clinician finds you ineligible. Affiliate code GOALS10 may take 10% off a new program. |
|
SHED Check price ↗ affiliate link | From $149 a month | From $199 a month | Two-month minimum. Includes a care team with a nurse, health coach and registered dietitian, plus the Pivot tracking app. |
| Gala Health Check price ↗ affiliate link | Not listed separately | $149 a month on a yearly plan | Sold as a GLP-1/GIP microdose on a yearly subscription. Gala's app site shows $149; its own microdosing page repeats its standard $179, so confirm at checkout. |
|
Lemonaid Health Check price ↗ affiliate link | $199 a month | $199 a month | Plus a $49 monthly membership (first month free). Fees are non-refundable once paid. |
What the first three months cost
Microdose plans are usually sold as an ongoing program, so the first three months are a fairer comparison than a single month.
| Provider | Semaglutide, 3 months | Tirzepatide, 3 months | How we calculated it |
|---|---|---|---|
| CoreAge Rx | $237 | $387 | Starting monthly price × 3 |
| PlexusDx | $267 | $267 | 3-month plan, $89 × 3 |
| bmiMD | $357 | $477 | Published 3-month plan total |
| SHED | $447 | $597 | Starting monthly price × 3 |
| Gala Health | — | $447 | $149 × 3, but sold on a yearly plan |
| Lemonaid Health | $695 | $695 | $199 × 3 plus two months of membership |
These are our sums from published starting prices. Your price can be higher if a provider charges more for higher doses or adds fees at checkout.
CoreAge Rx has the lowest published microdose prices we found.
See CoreAge Rx plans ↗Affiliate link. Final pricing and prescription eligibility are confirmed by the provider.
What microdosing is, and what the evidence says
There is no standard definition of a GLP-1 “microdose.” The providers above describe it as a smaller-than-usual dose of compounded semaglutide or tirzepatide, set by their clinicians. None of their pages lists a specific milligram dose.
The approved drugs, Wegovy and Zepbound, start at low doses only as a step toward a higher maintenance dose. Staying at a very low dose long term has not been studied in clinical trials. Doctors and researchers interviewed by STAT in November 2025 said there is little clinical proof that tiny doses of semaglutide or tirzepatide deliver the benefits telehealth companies advertise.
Questions to ask before you start
- What dose will I take, in milligrams, and how often? “Microdose” alone doesn’t tell you.
- How long does one vial last at that dose? This turns a monthly price into a cost per dose.
- What happens to the price if I move to a standard dose? SHED’s help center, for example, says doses above 0.9 mg move you to a $299 Standard plan.
- Is there a minimum commitment? SHED requires two months; bmiMD’s best price needs a 3-month plan.
Common questions
What is the cheapest microdose GLP-1 program?
CoreAge Rx, from $79 a month for semaglutide and $129 for tirzepatide, among the programs we checked on October 24, 2026.
Is GLP-1 microdosing FDA-approved?
No. Compounded semaglutide and tirzepatide are not FDA-approved, and taking them at low doses for “metabolic” or longevity goals is off-label.
Does microdosing cause fewer side effects?
Lower doses of GLP-1 drugs generally cause fewer stomach side effects in the approved drugs’ titration schedules, but microdosing itself has not been tested in trials, so there is no reliable data on its benefits or risks.
Can I switch from a microdose to a full dose later?
Usually, yes, after a clinician review, but the price may change. Ask before you prepay a multi-month plan.
Compare more GLP-1 options
- Compounded semaglutide price comparison
- Compounded tirzepatide price comparison
- Oral GLP-1 providers compared
- Best GLP-1 telehealth providers
How we sourced this
Prices and plan terms were read from each provider’s own microdose pages on October 24, 2026. Where a page showed several plan lengths, we report the price it displays by default and say which plan it applies to.
- CoreAge Rx semaglutide microdosing: coreagerx.com/product/semaglutide-microdosing-therapy
- CoreAge Rx tirzepatide microdosing: coreagerx.com/product/tirzepatide-microdosing-therapy
- bmiMD semaglutide microdose: bmimd.com/glp-1-microdose/
- bmiMD tirzepatide microdose: bmimd.com/glp-1-gip-microdose
- SHED microdose GLP-1: tryshed.com/products/microdose
- SHED help center: microdose GLP-1: help.tryshed.com/en/articles/13064878-microdose-glp-1
- SHED help center: subscription programs and pricing: help.tryshed.com/en/articles/12207572-shed-subscription-programs-and-pricing
- Lemonaid weight-loss program: lemonaidhealth.com/services/weight-loss
- STAT: microdosing GLP-1 drugs lacks clinical evidence (November 4, 2025): statnews.com/2025/11/04/microdosing-glp-1-drugs-no-clinical-evidence-effective/
This is consumer information, not medical advice. Talk to a licensed clinician about whether a GLP-1 is right for you. Send a correction.