What this covers
- Compounded semaglutide, every provider, cheapest first
- Compounded semaglutide is not Ozempic or Wegovy
- Dose escalation is the hidden price rise
- Injectable, tablet, sublingual and dissolving — they are not the same product
- Two providers publish a price with no billing period
- Who each price band suits
- How we sourced this
- Related comparisons and guides
Eleven of the twelve providers we track sell a compounded semaglutide preparation, and the annual cost ranges from roughly $948 to roughly $3,588 for the same molecule. That is a spread of nearly four to one, and almost none of it is explained by the medication itself.
What explains it is the billing interval, whether the headline number is promotional, and whether the provider charges more as your dose goes up. Four providers state plainly that every dose costs the same. One states that price varies by dose. The rest do not say.
Check current Trimi Health pricing Compare all twelve providers
The Trimi Health link is an affiliate link. The comparison link is not.
Compounded semaglutide, every provider, cheapest first
Ro is not in this table. Ro is built around FDA-approved branded medication, including the Wegovy pill, and does not sell a compounded preparation. Everyone else here does.
| Provider | Form | Advertised price | Billing cycle | Annualised cost | Does the price rise with your dose? |
|---|---|---|---|---|---|
| Embody | Injectable compounded semaglutide | $79 / month (promotional) | Monthly | ~$948 | Not stated on the product page |
| WellMedr | Injectable compounded semaglutide | $59 | Every 21 days | ~$1,025 | Priced by medication, not by dose |
| Trimi Health | Injectable compounded semaglutide | $99 / month | Monthly | $1,188 | All doses the same price |
| CoreAge Rx | Injectable compounded semaglutide | $99 / month | One-time purchase | ~$1,188 | All doses the same price |
| Oak | Injectable compounded semaglutide | from $119 / month (FAQ); $190 / month on its own chart | Subscription, renews | ~$1,428 – $2,280 | Not stated |
| Bodybuilding Health+ | Injectable compounded semaglutide | $139–$179 / month by term | 1, 3, 6 or 12-month terms | $1,668 – $2,148 | Priced by term length, not by dose |
| TrimRx | Injectable compounded semaglutide | from $179 / month | Recurring subscription | ~$2,148 | Priced by medication, not by dose |
| SkinnyRx | Injectable or tablet compounded semaglutide | from $199 / month ("as low as") | Auto-renewing monthly | ~$2,388 | Not stated |
| Synergy Rx | Injectable compounded semaglutide | $199 | Not stated anywhere on the site | ~$2,388 if monthly | Not stated |
| Care Bare Rx | Oral semaglutide (sold under the Rybelsus brand name) and injectable compounded semaglutide | “from $199” on the home page; the weight-loss page lists no prices at all | Not stated anywhere on the site | ~$2,388 if monthly | FAQ says price varies by dose |
| Direct Meds | Sublingual compounded semaglutide | from $249 / month | Every 30 days | ~$3,030 | Not stated |
| Synergy Rx | Semaglutide oral dissolving tablet | $299 | Not stated anywhere on the site | ~$3,588 if monthly | Not stated |
Compounded semaglutide is not Ozempic or Wegovy
This matters more than any price in the table. Ozempic and Wegovy are FDA-approved products made by Novo Nordisk. A compounded semaglutide preparation is made up by a compounding pharmacy for one named patient, and the FDA has not reviewed it for safety, effectiveness or manufacturing quality. It is not a generic version of an approved drug and should not be treated as one.
Most of these companies say so themselves, though usually in a safety notice rather than next to the price. TrimRx's terms state it in plain language. WellMedr carries the notice on its weight-loss page. Trimi and CoreAge Rx put the word "compounded" in the product name, which is the most honest placement. Care Bare Rx carries the disclaimer and then quotes clinical trial results from FDA-approved Ozempic on a page selling a compounded product, which is the least honest we found.
Our full explainer is compounded vs FDA-approved GLP-1s, and the legal position is covered in is compounded semaglutide legal.
Dose escalation is the hidden price rise
Semaglutide treatment normally starts low and steps up over several months. If a provider prices by dose rather than by medication, your bill goes up on a schedule you cannot control — and that increase will not appear anywhere in the price you were quoted at signup.
Trimi Health and CoreAge Rx both state that every dose costs the same. WellMedr and TrimRx price by medication type rather than dose. Care Bare Rx's FAQ says the opposite: price varies by dose and by medication prescribed, on a page that lists no prices at all. The remaining providers simply do not address it, which is not the same as saying it will not happen.
If a provider does not publish a dose-by-dose price list, ask before you pay: what will this cost me at the maintenance dose, not the starting dose? Get the answer in writing. Titrating up is the normal course of treatment, not an edge case.
Injectable, tablet, sublingual and dissolving — they are not the same product
Four different delivery formats appear in the table above. Injectable compounded semaglutide is what most of these providers sell. SkinnyRx offers a tablet. Synergy Rx sells an oral dissolving tablet at $299. Direct Meds sells a sublingual preparation at $249. Care Bare Rx sells oral semaglutide under the Rybelsus brand name alongside an injectable compounded option.
Oral semaglutide is a real, FDA-approved route in the branded product, so the format is not inherently suspect. But the oral and sublingual compounded options in this table are consistently the most expensive per year, and none of the providers selling them publish comparative absorption or dosing data. We cover the trade-offs in our oral GLP-1 provider comparison.
Two providers publish a price with no billing period
Synergy Rx displays $199 for compounded semaglutide and $299 for the oral dissolving tablet. Care Bare Rx advertises weight-loss treatment from $199. Neither site states, anywhere we could find, whether those are one-off charges, monthly charges or something else. Synergy Rx's terms of use contain no mention of subscriptions, renewals or recurring billing at all.
Both sets of terms are dated 1 January 2024, both are written throughout for a brand called CareGLP rather than for the site you are on, and both contain the same clause warning that the final charge to your credit card "may fluctuate". They also list the same physicians, with the same NPI numbers, and the same four compounding pharmacies. We think it is reasonable to read them as one operation with two storefronts.
Full detail is in the Synergy Rx review and the Care Bare Rx review.
Who each price band suits
The $79–$119 band is reasonable if
- You are comfortable with a compounded preparation and have read what that means.
- You will diarise the renewal date. Embody asks for 72 hours' notice; WellMedr publishes two different notice periods.
- You can tolerate a promotional price ending, because Embody's $79 sits under a site-wide promo banner with no published end date.
- You want the arithmetic to be simple — Trimi Health at $99 and CoreAge Rx at $99 are the two plans here whose headline price is also the real monthly price.
Paying $199 or more only makes sense if
- You specifically want an oral or sublingual format and have discussed it with a clinician.
- The provider is giving you something concrete for the difference, such as Direct Meds' dedicated nurse check-ins.
- You have confirmed the billing interval in writing, which two providers in this band do not publish.
- You have read the refund policy, because at this price a single non-refundable cycle costs more than a month of the cheapest plan.
See CoreAge Rx current pricing Read our cheapest-provider ranking
The CoreAge Rx link is an affiliate link. The ranking link is not.
How we sourced this
We read every figure above from the provider's own public pages — product and pricing pages, FAQs, terms of use and refund or cancellation policies — on 11 August 2026, and we annualised them ourselves using the billing interval each provider publishes. We have not been through any provider's checkout, so we are reporting what the documents say rather than what a bank statement shows. Where a provider does not publish a billing interval we say so instead of guessing, and the annual figure in that row assumes monthly billing purely so the row is comparable. Providers change pricing often. If you find a discrepancy, tell us on our contact page and we will check it and update the row.
Related comparisons and guides
- Compounded tirzepatide prices compared
- Cheapest GLP-1 telehealth in 2026, annualised
- Refund and cancellation policies compared
- Providers that do not put you on a subscription
- Compounded vs FDA-approved GLP-1s
Medical note
This is consumer purchasing information, not medical advice. GLP-1 medicines are prescription drugs with real risks and real contraindications, and nothing on this page has been clinically reviewed. Talk to a clinician who knows your history before starting, changing or stopping treatment. See our medical disclaimer.