What this covers
- Billing model by provider
- The only true no-subscription option, and its catch
- "No subscriptions" that are subscriptions
- The 21-day cycle is the most expensive detail in this market
- Renewals that can be charged early
- The two providers that publish no billing model at all
- How to protect yourself on any recurring plan
- How we sourced this
- Related comparisons and guides
Only one of the twelve providers we track sells GLP-1 treatment as a genuine one-time purchase with nothing renewing behind it: CoreAge Rx. Bodybuilding Health+ sells prepaid terms. Everything else is a subscription, and two providers do not tell you what their billing model is at all.
The number that matters is not "monthly". It is how many times a year the card is charged. That figure ranges from one to about 17.4 across this table, and in two cases it is genuinely unknown because the provider does not publish it.
Check current CoreAge Rx pricing Compare all twelve providers
The CoreAge Rx link is an affiliate link. The comparison link is not.
Billing model by provider
Ordered from least recurring to most, with the two providers that publish nothing at the bottom.
| Provider | Billing model | Charges per year | Notice needed to stop | Where we found it |
|---|---|---|---|---|
| CoreAge Rx | One-time purchase. Nothing renews on its own; refills are ordered manually. | As many as you choose to place | None — there is nothing to cancel, but see the warning below about early exit from 6 and 12-month plans | Product pages and refund policy |
| Bodybuilding Health+ | Prepaid term of 1, 3, 6 or 12 months, priced per tier | 1 per term | Not described in the pricing we hold; terms state all sales are final | Pricing page |
| Ro | Membership, monthly or prepaid annually. Medication billed separately and not capped. | 12, or 1 if prepaid annually, plus medication charges | Not published in our summary; membership cancellation is handled in-account | Membership pricing page |
| Trimi Health | Monthly subscription | 12 | Cancel before a clinician writes the prescription for a full refund including the consultation fee | Refund policy |
| Embody | Monthly subscription | 12 | 72 hours before renewal. A late cancellation charges you for the next cycle and defers your exit by a full cycle. | Cancellation policy |
| TrimRx | Recurring subscription | 12 | Effectively closes when the box ships. Refunds only for medical ineligibility or a TrimRx billing error, in writing within 28 days. | Terms and refund policy |
| SkinnyRx | Auto-renewing monthly, and the renewal may be charged up to 5 days early | 12, on dates you cannot fully predict | Not stated as a fixed window; cancelling a promotional term can reverse the discount | Subscription terms |
| Oak | Subscription that renews. Billing continues until the card declines, your health information changes, a new lab test is required, you cancel in the portal, or you delete the account. | 12 | Cancel in the portal before the next renewal. Once an order reaches the pharmacy it cannot be stopped. | Terms of use |
| Direct Meds | Subscription charged every 30 days — about 12.17 charges a year — despite an FAQ that says there are no subscriptions | ~12.17 | 48 hours before the next processing date, via the auto-refill toggle. Direct Meds says it notifies you 5–7 days in advance. | Terms section 5 |
| WellMedr | Auto-renewing every 21 days — about 17.4 charges a year | ~17.4 | The same policy page gives two different deadlines: 48 hours in one section, 72 hours in another | Refund and cancellation policy |
| Synergy Rx | Not stated. The terms of use contain no mention of subscriptions, renewals or recurring billing. | Unknown | Unknown — no refund policy or cancellation window is published | Nothing published |
| Care Bare Rx | Not stated. No billing period appears on the home page, the product page or in the terms. | Unknown | Unknown. The terms warn the final charge to your card “may fluctuate”. | Nothing published |
The only true no-subscription option, and its catch
CoreAge Rx sells compounded semaglutide at $99 and compounded tirzepatide at $149 as one-time purchases. There is no auto-renewal to forget about and no cancellation deadline to miss, which removes the single most common way people lose money in this market.
The catch is on the other side. Buy a 6 or 12-month plan — which are structured as multiples of a 3-month supply — and change your mind partway through, and CoreAge Rx re-bills the medication already shipped at the higher 3-month rate. So the discount is not really a discount until the term is complete; it is a rebate you forfeit by leaving. The consultation fee of $50 to $100 is separately non-refundable under the refund policy, even though the FAQ on the same site promises a full refund to anyone a clinician declines.
That contradiction is unresolved on their own site. Details are in our CoreAge Rx review.
"No subscriptions" that are subscriptions
Direct Meds markets itself with the line that there are no subscriptions and no surprise charges. Section 5 of its own terms is headed Subscription Products and describes charges every 30 days, cancellable up to 48 hours before the next processing date using an auto-refill toggle, with 5 to 7 days of advance notice.
We do not think both statements can be true. The terms are the enforceable document, so treat the plan as recurring, find the auto-refill toggle on day one, and note that a 30-day cycle produces about 12.17 charges a year rather than twelve. On the $249 sublingual plan that is roughly $3,030 a year, not $2,988. On the $297 injectable plan it is roughly $3,614.
To their credit, Direct Meds publishes the notice period, the toggle mechanism and the advance-notification commitment, which is more than most. Full detail in the Direct Meds review.
The 21-day cycle is the most expensive detail in this market
WellMedr renews every 21 days. There are about 17.4 twenty-one-day periods in a year. That converts a $59 plan into roughly $1,025 a year and a $99 plan into roughly $1,721 — an increase of about 45 per cent over what a monthly reading of the same numbers would suggest.
It also means the renewal date moves every cycle. Twelve monthly renewals land on roughly the same date each month; seventeen 21-day renewals land on seventeen different dates. Combined with a cancellation policy that gives two different notice periods in two places on the same page, that is a genuinely hard subscription to exit cleanly. Our WellMedr review sets out both deadlines.
Renewals that can be charged early
SkinnyRx's subscription terms state the renewal may be charged up to five days before the renewal date. If you plan to cancel in the last week of a cycle, that window can close before you expect it to. The practical rule is to treat your renewal date as five days earlier than the one shown in your account.
Oak's terms go further in a different direction: billing continues until the card declines, your health information changes, a new lab test is required, you cancel in the portal, or you delete the account. And once a provider has approved an order and it has reached the pharmacy, Oak states it cannot be cancelled or refunded — explicitly including attempts to reroute, refuse or return the parcel through the carrier.
The two providers that publish no billing model at all
Synergy Rx and Care Bare Rx both display prices with no period attached, and neither set of terms describes subscriptions, renewals or recurring billing. Both documents are dated 1 January 2024, both are written throughout for a brand called CareGLP, and both carry an identical clause warning that the final charge to your card "may fluctuate". They also name the same physicians, with the same NPI numbers, and the same four compounding pharmacies.
A clause that lets the final charge to your card vary, combined with no published billing interval and no published refund policy, is the weakest documentation we found across all twelve providers. If you use either of these, ask for the billing interval and the cancellation method in writing before you enter a card, and keep the reply.
How to protect yourself on any recurring plan
- Find the billing interval in the terms before you pay, not after. Search the page for the words renew, billing, cancel and refund.
- Multiply the charge across 365 days using that interval, not across twelve months.
- Put the cancellation deadline in your calendar with four days of margin, not one.
- Cancel in writing as well as in the app, and keep the confirmation. An in-account toggle alone is hard to evidence in a card dispute.
- Check whether the consultation fee is refundable separately from the medication. On several of these providers it is not.
- Screenshot the price and the terms on the day you sign up. Promotional pricing here changes without notice.
Our step-by-step walkthrough for each provider is in how to cancel a GLP-1 subscription.
See Direct Meds current plans Compare refund policies
The Direct Meds link is an affiliate link. The comparison link is not.
How we sourced this
We read every figure above from the provider's own public pages — product and pricing pages, FAQs, terms of use and refund or cancellation policies — on 11 August 2026, and we annualised them ourselves using the billing interval each provider publishes. We have not been through any provider's checkout, so we are reporting what the documents say rather than what a bank statement shows. Where a provider does not publish a billing interval we say so instead of guessing, and the annual figure in that row assumes monthly billing purely so the row is comparable. Providers change pricing often. If you find a discrepancy, tell us on our contact page and we will check it and update the row.
Related comparisons and guides
- Refund and cancellation policies compared
- Cheapest GLP-1 telehealth in 2026, annualised
- Compounded semaglutide prices compared
- How to cancel a GLP-1 subscription
Medical note
This is consumer purchasing information, not medical advice. GLP-1 medicines are prescription drugs with real risks and real contraindications, and nothing on this page has been clinically reviewed. Talk to a clinician who knows your history before starting, changing or stopping treatment. See our medical disclaimer.