What this covers
- Every price, annualised, cheapest first
- Why the cheapest advertised price is almost never the cheapest plan
- The $59 plan that costs about $85 a month
- The cheapest plan with no subscription attached
- Where cheap gets expensive: the terms
- Who each end of the table suits
- How we sourced this
- Related comparisons and guides
On advertised price the cheapest compounded semaglutide we found is Embody at $79 a month. On annualised price the ranking changes, because WellMedr's $59 is billed every 21 days rather than monthly, which is roughly 17.4 charges a year instead of 12.
The cheapest provider whose headline number is also its real number is Trimi Health at $99 a month, or $1,188 a year, with CoreAge Rx at the same price and no subscription at all. The most expensive compounded plan in this comparison, Synergy Rx tirzepatide, would cost around $4,188 a year — roughly four and a half times the cheapest — for a preparation of the same molecule.
Check current Embody pricing See the full twelve-provider table
The Embody link is an affiliate link. The comparison link is not.
Every price, annualised, cheapest first
This is the same twelve providers as our main comparison, but with each plan broken out by medication and multiplied across a full year using the billing interval the provider publishes. A tilde means we calculated the number rather than read it.
| Provider | Medication | Advertised price | Billing cycle | Our annualised cost | Effective per calendar month |
|---|---|---|---|---|---|
| Embody | Compounded semaglutide | $79 / month (promotional) | Monthly | ~$948 | ~$79 |
| WellMedr | Compounded semaglutide | $59 | Every 21 days | ~$1,025 | ~$85 |
| Trimi Health | Compounded semaglutide | $99 / month | Monthly | $1,188 | $99 |
| CoreAge Rx | Compounded semaglutide | $99 / month | One-time purchase, refills ordered manually | ~$1,188 | ~$99 |
| Oak | Compounded semaglutide | from $119 / month (FAQ) | Subscription, renews | ~$1,428 | ~$119 |
| Trimi Health | Compounded tirzepatide | $125 / month | Monthly | $1,500 | $125 |
| Embody | Compounded tirzepatide / GIP | $129 / month (promotional) | Monthly | ~$1,548 | ~$129 |
| Bodybuilding Health+ | Compounded semaglutide | $139–$179 / month | 1, 3, 6 or 12-month terms | $1,668 – $2,148 | $139–$179 |
| WellMedr | Compounded tirzepatide | $99 | Every 21 days | ~$1,721 | ~$143 |
| CoreAge Rx | Compounded tirzepatide | $149 / month | One-time purchase | ~$1,788 | ~$149 |
| Bodybuilding Health+ | Compounded tirzepatide | $159–$209 / month | 1, 3, 6 or 12-month terms | $1,908 – $2,508 | $159–$209 |
| TrimRx | Compounded semaglutide | from $179 / month | Recurring subscription | ~$2,148 | ~$179 |
| Oak | Compounded semaglutide | $190 / month (its own comparison chart) | Subscription, renews | ~$2,280 | ~$190 |
| SkinnyRx | Compounded semaglutide | from $199 / month | Auto-renewing monthly, up to 5 days early | ~$2,388 | ~$199 |
| Synergy Rx | Compounded semaglutide | $199 — no billing period stated | Not published anywhere on the site | ~$2,388 if monthly | ~$199 |
| Care Bare Rx | Weight loss, medication not specified on the home page | “starting at $199” — no billing period stated | Not published anywhere on the site | ~$2,388 if monthly | ~$199 |
| Direct Meds | Sublingual compounded semaglutide | from $249 / month | Every 30 days | ~$3,030 | ~$253 |
| TrimRx | Compounded tirzepatide (GLP-1 + GIP) | from $259 / month | Recurring subscription | ~$3,108 | ~$259 |
| SkinnyRx | Compounded tirzepatide | from $299 / month | Auto-renewing monthly | ~$3,588 | ~$299 |
| Synergy Rx | Semaglutide oral dissolving tablet | $299 — no billing period stated | Not published | ~$3,588 if monthly | ~$299 |
| Direct Meds | Injectable compounded GLP-1 | from $297 / month | Every 30 days | ~$3,614 | ~$301 |
| Synergy Rx | Compounded tirzepatide | $349 — no billing period stated | Not published | ~$4,188 if monthly | ~$349 |
| Ro | FDA-approved branded GLP-1 — membership only, medication billed separately | $39 first month, then $149 / month, or as low as $74 / month prepaid annually | Monthly, or annually if you prepay | $888 – $1,788 membership alone | $74–$149 |
| WellMedr | Brand-name Ozempic (FDA-approved), cash pay | from $1,399 / month | Monthly | ~$16,788 | ~$1,399 |
Four rows above carry an asterisk in everything but name. Synergy Rx and Care Bare Rx publish prices with no billing period attached anywhere on their sites — not on the product page, not in the FAQ, not in the terms of use. We have assumed monthly so the row can be compared, but that assumption is ours, not theirs. If you are considering either, get the billing interval in writing before you enter a card.
Why the cheapest advertised price is almost never the cheapest plan
Three mechanics move the real number, and none of them appear next to the headline price.
The billing interval. A month is not a fixed unit in this market. WellMedr renews every 21 days. Direct Meds renews every 30 days. Both describe themselves in monthly language. Twenty-one days gives you about 17.4 charges a year; thirty days gives you about 12.17. Only a true calendar month gives you twelve.
Promotional pricing. Embody's $79 and $129 sit under a site-wide promotional banner. Synergy Rx displays a "2026 Promo Applied" banner over its prices. A promotional rate is a real price for as long as it lasts, but it is not a rate you can plan a year of treatment around, and none of these companies publish an end date.
What is actually included. Ro's $149 is a membership fee. The medication is not in it. That is not a criticism — Ro is the only provider here built around FDA-approved branded product and an insurance claim — but it means the $149 row and the $99 row are not two prices for the same thing.
The $59 plan that costs about $85 a month
WellMedr advertises compounded semaglutide from $59 a month and describes shipments arriving every four weeks. Its refund and cancellation policy states that the subscription automatically renews every 21 days. There are roughly 17.4 twenty-one-day periods in a year, not twelve.
If the renewal amount is $59, a year costs in the region of $1,025 rather than $708. That still makes it one of the cheaper plans in this table — it is not a scam and we are not calling it one — but it is not the cheapest, and it is not $59 a month. We have not been billed by WellMedr ourselves, so we are reporting the policy rather than a statement. Anyone signing up should ask in writing how many times a year the card is charged and at what amount.
Read the full WellMedr review for the two contradictory cancellation deadlines on the same policy page.
The cheapest plan with no subscription attached
CoreAge Rx sells compounded semaglutide at $99 and tirzepatide at $149 as one-time purchases rather than a subscription, with refills ordered manually. On annual cost it ties with Trimi Health, and it is the only provider in this comparison where nothing renews on its own.
There is a catch worth knowing before you treat that as a clean win. Buy a 6 or 12-month plan and cancel early, and CoreAge Rx re-bills medication already shipped at the higher 3-month rate. Its consultation fee of $50 to $100 is also non-refundable under the refund policy, even though the FAQ on the same site promises a full refund to anyone a provider declines. Details are in our CoreAge Rx review.
Where cheap gets expensive: the terms
Price and refund generosity are not correlated in this market. Trimi Health is near the bottom of the price table and has the most generous pre-prescription refund policy we read, returning the consultation fee as well as the medication cost if a clinician declines you. Bodybuilding Health+ publishes every price tier openly and attaches an all-sales-final policy to them. Oak's terms state that once a provider approves your order and it reaches the pharmacy it cannot be cancelled or refunded, explicitly including attempts to reroute or refuse the parcel with the carrier.
Before you rank on price alone, put the refund column next to it. We have done that on our refund and cancellation comparison.
Who each end of the table suits
Going for the cheapest number makes sense if
- You have already decided that a compounded preparation is acceptable to you, and you understand it is not FDA-approved.
- You can absorb a full cycle's charge if you cancel late, because most of these providers will not refund it.
- You are willing to diarise the renewal date and cancel with several days in hand.
- You are buying semaglutide rather than tirzepatide, where the spread between providers is narrower in absolute dollars.
Pay more, or look elsewhere, if
- You want the FDA-approved branded product. Only Ro is built around that, and WellMedr's cash-pay Ozempic is roughly $16,800 a year.
- You have insurance that might cover a branded GLP-1, in which case an insurance-first provider can beat every cash price here.
- You need a published billing interval and refund window before you will enter a card — two providers here do not publish one.
- You expect to stop within a few weeks. On most of these plans the money is gone the moment a clinician signs the prescription.
See Trimi Health current pricing Compare all twelve providers
The Trimi Health link is an affiliate link. The comparison link is not.
How we sourced this
We read every figure above from the provider's own public pages — product and pricing pages, FAQs, terms of use and refund or cancellation policies — on 11 August 2026, and we annualised them ourselves using the billing interval each provider publishes. We have not been through any provider's checkout, so we are reporting what the documents say rather than what a bank statement shows. Where a provider does not publish a billing interval we say so instead of guessing, and the annual figure in that row assumes monthly billing purely so the row is comparable. Providers change pricing often. If you find a discrepancy, tell us on our contact page and we will check it and update the row.
Related comparisons and guides
- Compounded semaglutide prices compared — semaglutide only, every provider that sells it.
- Compounded tirzepatide prices compared — where the spread is widest.
- GLP-1 providers without a subscription — who bills once and who bills forever.
- Refund and cancellation policies compared — the window closes earlier than you think.
- Oral and sublingual GLP-1 providers — tablets, dissolving tablets and what they cost.
- GLP-1 cost without insurance in 2026 — the long-form version of the arithmetic above.
Medical note
This is consumer purchasing information, not medical advice. GLP-1 medicines are prescription drugs with real risks and real contraindications, and nothing on this page has been clinically reviewed. Talk to a clinician who knows your history before starting, changing or stopping treatment. See our medical disclaimer.